Product description
Retinoin is a natural or synthetic derivative of vitamin A, belonging to the retinol class of compounds. It is primarily used to regulate skin cell growth, differentiation, and metabolism. It is a common prescription dermatology medication suitable for conditions such as acne and psoriasis, but must be used strictly according to a doctor's instructions.
Retinoic acid is obtained by chemically modifying vitamin A. It is available in natural extracts (such as all-trans retinoic acid) and synthetic forms. It regulates gene expression by binding to receptors in the cell nucleus.
In dermatology, tretinoin is the accepted gold standard for treating acne and promoting research on cellular anti-aging. Ultra-pure Tretinoin that closely complies with the strictest international pharmaceutical monographs is offered by TIANJIN YINAO.
Grade: Pharmaceutical Grade (Fully compliant with USP and EP standards).
Purity: 98.0% – 102.0% (Assay on dried basis via HPLC).
CAS Number: 302-79-4
Documentation: Full technical dossier available, including COA, HPLC chromatograms, Infrared Absorption (IR), and MSDS.
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COA |
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product name |
Tretinoin |
Lot number |
YA20251001 |
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Quantity |
200KG |
Date of manufacture |
2025.10.05 |
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Examination date |
2025.10.13 |
Effective data |
2027.10.01 |
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Item |
Acceptable Criteria |
Results |
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Appearance |
Yellow or litht-orange crystalline |
Light-oranee crystalline powder |
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ldentifcation |
The IR speetrum ofthe sample should correspond tothat ofthe reference standard |
Qualified |
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Compared with there reference standard. Absorptivities of the sample at 352nm should not differ bymore than 3.0% |
Qualified |
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Residue on lgmton |
≤0.1% |
0.05% |
Qualified |
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loss on drying |
≤0.5 |
0.1% |
Qualified |
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Assay |
97.0%~ 103.0% |
100.5% |
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Conclusion: The product passed the test. |
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Function
Regulates cell differentiation: Promotes normal keratinization of epidermal cells and reduces follicle blockage.
Inhibits inflammatory response: Reduces inflammation caused by Propionibacterium acnes.
Accelerates metabolism: Helps shed dead skin cells and improves skin texture.
Application:
Cosmetic grade;
Medical grade.

GMP Certified Production
The production environment is the main quality indicator for pharmaceutical procurement. GMP (Good Manufacturing Practice) accredited facilities are the exclusive source of tretinoin from TIANJIN YINAO.
- Audit-Ready Quality: With accessible Drug Master Files (DMF) and Site Master Files, our supply chain facilitates institutional audits.
- Impurity Control: Minimum amounts of residual solvents and associated chemicals that are guaranteed to meet pharmaceutical safety standards.
- Professional Logistics: To guarantee that the temperature stays constant from the production to your lab, cold-chain logistics services are available for large orders.

Critical Storage & Stability Protocol (Non-Negotiable)

Tretinoin is a very sensitive molecule that is vulnerable to heat instability and photodegradation. TIANJIN YINAO employs a laboratory-grade protection process to ensure 100% bioactivity upon delivery:
- Light Protection: To prevent all UV exposure, only amber glass vials or light-proof vacuum-sealed aluminum bags are used.
- Temperature Control: To avoid molecular isomerization, it must be transported and stored at low temperatures (usually -20°C or 2–8°C).
- Oxidation Barrier: To prevent oxidative deterioration during extended storage, it is sealed in an inert nitrogen atmosphere.
OEM&ODM
We offer a variety of dosage forms and neutral packaging, including mixed powders, granules, soft capsules, hard capsules, tablets, gummies, and more, to meet the diverse needs of our customers. Yinao is committed to providing customers with natural, safe, and organic plant extracts.






Certifications
The company consistently adheres to its corporate mission of creating a healthy life, strictly controls product quality, and holds certifications including ISO9001, Halal, and Kosher. It continuously innovates and develops, earning the high-tech enterprise certificate for several consecutive years.

Delivery & Shipping &Package
International Express-- Fedex/DHL/UPS, air shipping and sea shipping, double-clearance custom.

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Packaging Details |
10g/Bag,1Kg/bag/25kg/Drum,According to your requirements |
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Port |
China main port |

Why Choose Us

1. A supplier of botanical extracts with over 15 years of experience and almost 2000 product types!
2. Has several national invention patents and has spent more than 15 years concentrating on the creation of plant active substances.
3. International certification systems: Jewish, halal, organic, IP (non-GMO), ISO9001, ISO22000, and others.
4. A skilled and knowledgeable research and development team made up of academics from renowned universities and professionals with decades of industry experience.
5. Offer a variety of products: the products have been used by all of the main international companies in the areas of medications, functional foods, cosmetics, nutritional supplements, and animal nutrition.
FAQ
Q: How to start orders or make payments?
A: A: You can send your requirement here on line,or send your purchase order by email to us, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?
A: You can buy samples for some products,and there will be discount for sample, after testing our sample, if all is ok for you, when make bulk order, we can return the sample fee back to you, and you can also send us your requirement for some special item, we can found for you in our local market.
Q: What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 1kgs. For other low value product, our MOQ starts from 10kg and 100kg.
Q: Is there a discount?
A: Different quantity has different discount, for larger quantity, we alway support with better price.
Q: How to contact us?
A: You can chat with us by Whatsapp & Email & wechat Online. You can also choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
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