Vitamin K2 MK-7 & MK-4

Vitamin K2 is a collective term for a series of compounds known as menaquinones, which feature a 2-methyl-1,4-naphthoquinone core and a variable number of isoprene units at the C3 position. Depending on the number of carbon atoms in the isoprene side chain, vitamin K2 can be categorized into various forms such as K2(10), K2(20), K2(35), K2(40), and so forth.

Vitamin K2 is a fat-soluble vitamin that belongs to the naphthoquinone family and exhibits phylloquinone-like biological activity. It is an essential vitamin for human health.

Vitamin K2(35) refers to a specific form of vitamin K2 with a terpene side chain that contains 35 carbon atoms. It is also known as menadione-7, named for its seven isoprene units. Vitamin K2 is the biologically active form of vitamin K, primarily utilized to promote blood clotting, maintain normal clotting times, and treat bleeding disorders resulting from vitamin K deficiency.

Differentiating between the two main forms of vitamin K2 is crucial to ensuring pharmaceutical-grade precision and meeting international regulatory standards. For both compounds, TIANJIN YINAO offers standardized specifications:

Feature	Vitamin K2 (MK-7)	Vitamin K2 (MK-4)
Chemical Name	Menaquinone-7	Menatetrenone
Source	Natural Fermentation (Bacillus subtilis natto)	Synthetic (Identical to animal-source K2)
Biological Half-Life	Long (72+ hours): Stays in the blood for sustained systemic benefit.	Short (1-2 hours): Rapidly cleared by the liver.
Efficacy	Effective at microgram (mcg) doses.	Requires high milligram (mg) doses.
Primary Target	Arterial Decalcification & Bone Density.	Localized tissue support & Bone health.

From pharmaceutical research to retail supplements, we provide a wide variety of vitamin K2 concentrations.

Purity Grades:

• 0.2% / 1.0% (Standardized Powder): The multivitamin combination industry standard.
• 98.0% (Ultra-Pure / Marker Grade): for R&D and high-potency clinical trials.

Specialized Forms:

• CWS (Cold Water Soluble) Powder: Optimized for sachet mixes and RTD beverages.
• Vitamin K2 Oil (MCT or Olive Oil base): Designed for high-stability softgel encapsulation.

Through our bespoke granulation service, TIANJIN YINAO offers specialist DC (Direct Compression) Grade Vitamin K2 to large-scale manufacturers and tableting facilities.

The Stability Challenge: Because of its extreme sensitivity, vitamin K2 can break down when combined with alkaline minerals like calcium carbonate or magnesium oxide.

The Solution: The K2 molecule is shielded by our micro-encapsulation technique, guaranteeing label claim efficacy for the duration of the product's shelf life.

Custom Mesh Size: To meet your unique tablet press needs, we can modify the granulation (e.g., 40–80 mesh), guaranteeing superior flowability and no clumping.

[REQUEST CUSTOM GRANULATION SPECIFICATIONS]

1. Facilitates calcium deposition in bones: Vitamin K2 assists in the carboxylation of osteocalcin, a protein secreted by osteoblasts, into its active form. This process promotes the deposition of calcium ions from the blood into the bones. With adequate vitamin K2, osteocalcin becomes activated and exhibits a specific affinity for calcium ions, drawing them into the bones and facilitating the deposition of calcium salts, thereby enhancing bone mineralization.

 

2. Treats and prevents osteoporosis: Vitamin K2 contributes to the production of bone proteins that bind with calcium to form bone tissue, which increases bone density and helps prevent fractures.

3. Vitamin K2 can help prevent the progression of cirrhosis to liver cancer.

4. Treats vitamin K2 deficiency bleeding, promotes the formation of prothrombin, accelerates the coagulation process, and maintains normal coagulation times.

5. Possesses diuretic properties, enhances the liver's detoxification capabilities, and can assist in lowering blood pressure.

1. Research reagents: Used as intermediates in chemical synthesis or as experimental standards.

2. Nutritional fortifiers: Utilized as a source of vitamin K2 in food or health supplements.

3. Pharmaceutical raw materials: Employed in the research and development, as well as the production, of related drugs.

OEM&ODM

We offer a variety of dosage forms and neutral packaging, including mixed powders, granules, soft capsules, hard capsules, tablets, gummies, and more, to meet the diverse needs of our customers. Yinao is committed to providing customers with natural, safe, and organic plant extracts. 

Gummy

Granular

Blending Powder

Capsules(Hard Capsules & Soft Capsules)

Tablet & Effervescent Tablet

Liquid and oil

Certifications

The company consistently adheres to its corporate mission of creating a healthy life, strictly controls product quality, and holds certifications including ISO9001, Halal, and Kosher. It continuously innovates and develops, earning the high-tech enterprise certificate for several consecutive years.

 

International Express-- Fedex/DHL/UPS, air shipping and sea shipping, double-clearance custom.

1. More Than 15 Years Botanical Extract Supplier, and around 2000 kinds of products!
2. Focused on the development of plant active ingredients for more than 15 years and has a number of national invention patents.
3. International certification system: ISO9001, ISO22000, IP (non GMO), Jewish, halal, organic and other certification.
4. Professional and experienced r&d team: professors from famous universities and experts with decades of working experience in this industry.
5. Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

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