What is semaglutide?
Semaglutide (Ozempic) is prescribed for the management of type 2 diabetes. It works in combination with dietary changes and physical activity to help improve blood sugar control. The medication is also indicated to reduce the risk of serious cardiovascular events-such as heart attack, stroke, or cardiovascular death-in adults with type 2 diabetes who also have obesity or established cardiovascular disease.
For laboratory research use only.
| COA | ||
| Test items |
Specifications
|
Results |
|
MW by MS
|
4113.75
|
Conforms |
|
Purity by HPLC
|
>99%
|
99.324%
|
|
Peptide Content
|
N/A | N/A |
|
Moisture content
|
N/A | N/A |
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Acetic acid content
|
N/A | N/A |
|
Appearance
|
White to off-white lyophilized powder
|
Conforms |
|
Quantity
|
50mg
|
50.0mg |
HPLC&MS
| Sample Information | |
| Name | Semaglutide |
| Sequence |
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly- Gln-Ala-Ala-N6-[N-(17-carboxy-1-oxoheptadecyl-L-a-glutamyl[2- (2-aminoethoxy)ethoxy] acetyl[2-(2-aminoethoxy) ethoxy]acetyl] -Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
| PumpA | 0.1%Trifluoroacetic in 100% water |
| PumpB | 0.1%Trifluoroacetic in 100% acetonitrile |
| Total Flow | 1ml/min |
| Wavelength | 214nm |
| Analytial column type | Kromasil 100-5-C18 (4.6*250mm*5 μm) |
| Dissolution method | 100%H2O |
| Inj. Volume | 50ul |
| Time |
Module
|
Action | Value |
| 0.01 | Pumps | B.Conc | 45 |
| 20.00 | Pumps | B.Conc | 65 |
| 33.00 | Pumps | B.Conc | 100 |
| 38.00 | Pumps | B.Conc | 100 |
| 40.00 | Pumps | B.Conc | 45 |
| 50.00 | Controller | Stop |
| Dissolution method: | 15%ACN+85%H2O | Interface | ESI |
Prerod Bias
|
+4.5kv
|
| Date Acquired : | 13:20:49 | Nebulizing Gas Flow | 1.5L0/min | Detector | -0.2kv |
| Injection Volume : | 0.2ul | CDL Temp | 250℃ | T.Flow | 0.2ml/min |
| Block Temp : | 200 | CDL Volt | 0V | B.conc | 50%H2O/50%MEOH |
| Name | Semaglutide |
| Sequence | His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEA-AEEA-γ-Glu-17-carboxyheptadecanoyl)-Glu- Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
| Theoretical | 4113.64 |
| Observed | 4113.75 |
Function & Uses
Semaglutide works through multiple mechanisms to help manage blood sugar levels and support weight management:
1. Stimulates Insulin Secretion
It enhances the release of insulin from the beta cells of the pancreas after meals, which helps lower elevated blood glucose levels.
2. Suppresses Glucagon Secretion
By reducing the production of glucagon, semaglutide decreases glucose output from the liver, preventing unnecessary rises in blood sugar.
3. Slows Gastric Emptying
Delaying the rate at which food leaves the stomach helps slow digestion, increases the sensation of fullness, and supports reduced food intake and weight control.
4. Acts on Appetite Centers in the Brain
Semaglutide influences brain regions involved in regulating appetite, helping to reduce hunger and further supporting controlled food intake.
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Application
Approved Indications (Requires a doctor's prescription):
1.Type 2 Diabetes Mellitus (T2DM)
Used to control blood glucose, can be used alone or in combination with other antidiabetic drugs (such as metformin, SGLT2 inhibitors, etc.).
2. Semaglutide for weight loss;
Many doctors use semaglutide for weight loss.
Studies have shown that semaglutide can reduce appetite and significantly decrease body weight, so it is used in obese or overweight populations in some countries.
Not suitable for type 1 diabetes or patients with diabetic ketoacidosis.
|
Semaglutide |
GLP-1R+GCGR |
Dual agonists |
|
Suppress appetite |
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Higher standards, more reassuring protection
|
Packaging Details |
10g/Bag,1Kg/bag/25kg/Drum,According to your requirements |
|
Port |
China main port |
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FAQ
Q: What is the minimum order quantity (MOQ) for the products?
A: The MOQ varies depending on the product value. High-value products typically start at 1 gram or 1 kilogram, while low-value products generally start at 10 kilograms or 100 kilograms.
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A: For high-value products, we can accept very small orders, such as starting from 1 gram. However, for most products, we have standard MOQ requirements.
Q: How can I find out the MOQ for a specific product?
A: Detailed MOQ for each product will be provided when you inquire. Generally, it follows our MOQ structure based on product value.
Q: Are there any bulk purchase discount programs?
A: Of course. We have attractive discount policies for bulk purchases, and the specific discount depends on your purchase quantity.
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