Product introduction
BAM 15 (N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine) is a mitochondrial proton
uncoupling agent that functions by disrupting mitochondrial energy metabolism.
One of the most cutting-edge substances in metabolic research now is BAM-15, a highly selective mitochondrial uncoupler. In contrast to conventional uncouplers (like DNP), BAM-15 has an excellent safety profile and dramatically raises metabolic rate without posing a danger of fatal hyperthermia (overheating).
| Test Item | Specification | Typical Result |
| Product Name | BAM-15 | Conforms |
| Chemical Name | (2-fluorophenyl){6-[(2-fluorophenyl)amino]-1,2,5-oxadiazolo[3,4-b]pyrazin-5-yl}amine | Conforms |
| CAS NO. | 210302-17-3 | Conforms |
| Molecular Formula (MF) | C14H8F2N6O | Conforms |
| Molecular Weight (MW) | 314.25 g/mol | Conforms |
| Purity (HPLC) | ≥98.0% | 99.40% |
| Appearance | Light yellow to yellow solid powder | Yellow Powder |
| Solubility | Soluble in DMSO (≥15 mg/mL) | Conforms |
| Loss on Drying | ≤0.5% | 0.18% |
Comparing This Metabolic Modulator to Others
| Feature | BAM-15 | 5-Amino-1MQ |
SR9009 (Stenabolic) |
| Drug Class | Selective Mitochondrial Uncoupler | NNMT Inhibitor |
Rev-ErbA Agonist |
| Mechanism | Dissipates proton gradient | Blocks NNMT / Boosts NAD+ |
Regulates circadian genes |
| Safety | High (No hyperthermia) | High (Natural metabolic reg) |
Medium (Circadian risk) |
| Endurance Impact | Neutral to slightly positive | Significantly increased |
Significantly increased |
| Primary Focus | Stubborn fat / Fatty liver | Anti-aging / Muscle retention |
Athletes / Endurance |
| Administration | Oral / Injectable | Oral | Oral |
| Market Status | Advanced Research Grade | Research / Premium Suppl. | Research Grade |
Capsule Strengths in Markets
| Product Name | Standard Strength (Per Capsule) | Typical Daily Total | Notes |
| 5-Amino-1MQ | 50 mg / 100 mg | 50 mg - 150 mg |
50 mg is the most popular "entry-level" spec. |
| Tesofensine | 0.25 mg / 0.5 mg | 0.5 mg |
High Precision Required. 1 mg+ often causes insomnia. |
| BPC-157 | 250 mcg / 500 mcg | 500 mcg - 1000 mcg |
Note the unit is micrograms (mcg). Usually Arg-BPC. |
| BAM-15 | 10 mg / 20 mg | 10 mg - 40 mg |
Newer to market; doses kept low to assess tolerance. |
| SLU-PP-332 | 25 mg / 50 mg | 50 mg - 100 mg |
Based on animal-to-human equivalent conversions. |
| SR9009 | 10 mg / 20 mg | 20 mg - 30 mg |
Short half-life; usually split into 2-3 doses daily. |
Function
Reduction of Metabolic Efficiency: It renders mitochondria "inefficient" un generating ATP (energy). In order to sustain cellular function, the body must burn a lot more fat and glucose.
Increased resting energy expenditure is a result of aggressive fat loss. According to research, BAM-15 lowers body fat even in the absence of calorie restriction or increased exercise.
Liver Health (NAFLD/NASH): One of the main options for treating Non-Alcoholic Fatty Liver Disease, it is very successful at removing extra fat from the liver.
Insulin sensitivity directly combats metabolic syndrome by enhancing glucose tolerance and lowering systemic inflammation.
Safety Profile: BAM-15 eliminates the risk of hyperthermia since, in contrast to earlier uncouplers, it does not considerably raise body temperature even at large dosages.
application
Organ Protection
Protects against acute kidney ischemia-reperfusion injury by preserving mitochondrial function.
Reduces cold-induced microtubule damage in cellular models.
Neuroprotection
Inhibits transport-induced apoptosis in iPSC-derived retinal tissues, offering insights into retinal degenerative diseases.
Metabolic Regulation
Activates AMP--activated protein kinase (AM-PK), a key regulator of cellular energy homeostasis, with implications for metabolic syndrome and diabetes research.
Mitochondrial Research
Acts as a protonophore to uncouple mitochondrial oxidative phosphorylation, enabling studies on mitochondrial bioenergetics and dysfunction.
OEM&ODM
QUALITY ASSURANCE
Purity: ≥99% (HPLC).
Impurity Profile: Complies with ISO 9001 standards for research-grade compounds.
Note: BAM15 is a cutting-edge tool for investigating mitochondrial dynamics, metabolic diseases, and organ injury mechanisms. Its dual action as an uncoupler and AM-PK activator makes it invaluable for preclinical studies in nephrology, neurology, and metabolism.
For detailed protocols, bulk orders, or custom formulations, contact our scientific support team.
Certifications
Higher standards, more reassuring protection
Delivery & Shipping &Package
Higher standards, more reassuring protection
|
Packaging Details |
10g/Bag,1Kg/bag/25kg/Drum,According to your requirements |
|
Port |
China main port |
Why Choose Us?
Our core competitiveness lies in our professional R&D team, composed of renowned university professors and experts with decades of industry experience. Leveraging this team, the company has focused on the development of plant-based active ingredients for over fifteen years, obtaining numerous invention patents. We offer approximately 2,000 extract products and hold comprehensive international certifications. These high-quality products have been successfully applied in various industries, including pharmaceuticals, health supplements, cosmetics, animal nutrition, and functional foods.
FAQ
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