NAD (nicotinamide adenine dinucleotide), also known as coenzyme I, is composed of nicotinamide, adenine, and two ribose sugars linked by phosphodiester bonds. It exists in an oxidized form (NAD⁺) and a reduced form (NADH). It acts as an electron carrier in various enzymatic reactions, performing redox functions through the transfer of hydrogen ions (H-) and protons (H+).

All live cells contain the essential coenzyme beta-DPN. In cellular metabolism, it acts as a universal electron carrier. When it is oxidized (NAD+), it takes in electrons from other molecules to become reduced (NADH).

Property	Specification (Typical)
Storage Temperature	−20°C (Long-term) or 2−8°C (Short-term)
Absorbance Max (λmax)	260 nm
Moisture Content	≤8%
Heavy Metals	≤10 ppm
Solubility	Highly soluble in water (50 mg/mL); stable in acidic solutions, unstable in alkaline conditions.

Function & Uses

Redox Reaction Catalyst: It serves as a cofactor for hundreds of dehydrogenases, including lactate and alcohol dehydrogenase. Glycolysis, the TCA Cycle (Krebs Cycle), and the Electron Transport Chain all depend on it.
DNA Repair Substrate: PARP (Poly ADP-ribose polymerase) enzymes use it as their only substrate to identify and fix damaged DNA.
Sirtuin Activation (Longevity Pathway): Sirtuins (SIRT1-7), the "longevity proteins" that control gene expression, mitochondrial biogenesis, and cellular aging, require it as a co-substrate.
Calcium Signaling: It is a precursor to the second messenger involved in intracellular calcium mobilization, cyclic ADP-ribose (cADPR).

Application

A. Biocatalysis & Clinical Diagnostics

Diagnostic Reagents: An essential part of enzymatic test kits that detect liver function (ALT/AST), blood sugar, and lactate.
In commercial biocatalysis, enzymatic synthesis is used to create chiral intermediates and fine compounds when a redox cycle is necessary.

B. Dietary Supplements & Nutraceuticals & Anti-Aging

Cellular Revitalization: Promoted as a high-end supplement that increases systemic NAD+ levels with the goal of enhancing energy (ATP generation) and mental performance.
Formulations aimed at preventing age-related cognitive decline use neuroprotection.

C. Research in Life Science

Cell culture: Added to specialized media to examine metabolic flux in mammalian cells or to promote the development of some picky bacteria.
Enzyme Assays: A common reagent for NAD-dependent enzyme kinetic investigations.

D. Development of Pharmaceuticals

API Intermediate: Used in the production of specific medications, such as several metabolic regulators and antivirals.

Why Choose Us?

Our products have successfully entered the global market and are widely used by internationally renowned brands in the pharmaceutical, health supplement, cosmetics, animal nutrition, and functional food industries. As a supplier with over 15 years of experience, our company offers approximately 2,000 plant extracts. We focus on core technology research and development, holding multiple invention patents and relying on a team of professors and industry experts to ensure the international competitiveness of our products under a rigorous quality certification system.

product-1218-379

Certifications

The cornerstone of the company's steady development lies in its adherence to the mission of "creating a healthy life," its strict control over product quality, and its continuous investment in innovation. This has enabled it to not only obtain numerous international certifications but also to be recognized as a high-tech enterprise for many consecutive years.