Coenzyme Q10

Humans reach their peak ability to synthesize coenzyme Q10 at age 20 and maintain it until around age 50. [3] After that, it will decline year by year because the mitochondrial DNA material that stores coenzyme Q10 is damaged by oxygen free radicals, resulting in a reduction in the autonomous synthesis of coenzyme Q10. As a result, the metabolic function of human cells, especially heart cells, declines, and "old age" becomes apparent.

As we age, the skin's collagen's ability to resist damage from oxidative stimuli such as ultraviolet radiation declines. Long-term use of coenzyme Q10 can effectively prevent photoaging and reduce wrinkles around the eyes. This is because coenzyme Q10 penetrates the skin's growth layer, weakening the oxidative reaction to photons. With the assistance of tocopherol, it can activate specific phosphorylated tyrosine kinases, preventing oxidative damage to DNA, inhibiting the expression of collagenase in human skin fibroblasts under ultraviolet light irradiation, and protecting the skin from damage.

Extensive research suggests that coenzyme Q10 inhibits lipid peroxidation, reduces free radical generation, protects the active site and structure of superoxide dismutase (SOD) from free radical oxidative damage, increases the activity of SOD and other enzymes in the body, and inhibits oxidative stress-induced apoptosis, thus exhibiting significant antioxidant and anti-aging effects.

The Mitchell chemiosmotic hypothesis reveals the energy conversion process within organisms and the important role of coenzyme Q10 in the mitochondrial energy conversion system.

Coenzyme Q10 significantly promotes heart health, and adequate levels in the body are essential for proper muscle function. Biochemical analysis of muscle cell extracts revealed that when coenzyme Q10 concentrations are 20% below normal, the activity of mitochondrial complexes I+II and I+III is severely reduced. Several studies have clearly shown that coenzyme Q10 supplementation at 100-150 mg/day can significantly improve the condition of individuals suffering from muscle malnutrition. Many overweight individuals have very low coenzyme Q10 levels, and supplementation can help them lose weight because coenzyme Q10 accelerates fat metabolism, ensuring ample energy supply to the limbs and brain, resulting in increased energy levels.

Recent studies have shown that coenzyme Q10 has anti-tumor effects and is clinically effective in treating advanced metastatic cancer. It also has significant effects in preventing coronary heart disease, relieving periodontitis, treating duodenal and gastric ulcers, enhancing the body's immune function, and relieving angina.