Tirzepatide 30mg

Tirzepatide what is it?

Tirzepatide is a dual-targeted drug that acts as a GLP-1 and GIP receptor agonist and is licensed to treat type 2 diabetes. It controls blood sugar levels by inhibiting the release of glucagon, promoting the secretion of insulin, and postponing the emptying of the stomach. Tirzepatide may help with weight management in addition to its glycemic advantages.

A synthetic linear peptide with 39 amino acids, tirzepatide was created to investigate dual-receptor pathways. It is a powerful research ligand for examining metabolic signaling's synergistic effects.

Tirzepatide's distinct dual-agonism is defined by its structural integrity. Its chemical structure is intended for high-affinity binding across two different metabolic pathways, in contrast to single-receptor ligands:

• Sequence Architecture: To improve stability and resistance to DPP-4 enzymatic degradation, aminoisobutyric acid (Aib) was added at positions 2 and 13 to a 39-amino acid backbone based on the GIP sequence.
• Dual-Agonist Mechanism: It acts as a dual GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonist. To further solidify the peptide structure, the C-terminal portion is amidated.
• Acylation Technology: Attaching a C20 fatty diacid moiety to the lysine residue at position 20 via a linker is a crucial aspect of its structure. In research models, this acylation greatly increases the terminal half-life by facilitating albumin binding.
• Molecular Synergy: Tirzepatide enables researchers to examine the enhancement of nutrient-stimulated insulin production and the regulation of glucagon levels via separate but complementary routes by activating both GIP and GLP-1 receptors.

Tirzepatide activates both GIP and GLP-1 receptors, producing complementary effects that improve glycemic control and support weight management:

1. Promotes the Secretion of Insulin
It successfully lowers blood glucose levels by increasing the production of glucose-dependent insulin from pancreatic beta cells.
2. Inhibits the Secretion of Glucagon
By lowering glucagon output from pancreatic alpha cells, the drug helps avoid producing too much glucose.

3. Delays Gastric Emptying
By slowing gastric emptying, it moderates nutrient absorption and helps control postprandial glucose levels.

4. Reduces Appetite
Tirzepatide acts on central nervous system pathways to decrease hunger and food intake.

This multi-targeted approach enables comprehensive management of metabolic parameters.

To support large-scale longitudinal studies and international distribution, TIANJIN YINAO offers a competitive wholesale price ladder. Our pricing is structured to reward high-volume research commitments.

• Customization: We provide Custom Labeling (OEM) and Specific Lyophilization Ratios (e.g., 5 mg, 10 mg, 15 mg, 30 mg,50mg,60mg) based on your distribution needs for orders more than 1,000 vials.
• Verification: To confirm purity (>99%) and peptide content, all B2B orders come with a thorough Batch COA (HPLC + MS).

Lyophilized Form: Our Tirzepatide is provided as a vacuum-sealed, lyophilized powder for maximum stability.

Recommended Storage: -20°C for long-term (up to 2 years) or 2-8°C for short-term research phases.

Shipping: Dispatched in temperature-controlled, discreet packaging via FEDEX,USPS, double-clearance custom;

We offer a highly diversified product line, with approximately 2,000 plant extracts widely used in pharmaceuticals, dietary supplements, cosmetics, animal nutrition, and functional foods, serving many mainstream international brands. The company has over 15 years of professional experience, focusing on the development and innovation of plant-based active ingredients, and has obtained numerous national invention patents. We have established a comprehensive quality certification system to ensure our products meet the stringent requirements of the global market.

1. Send us the product CAS and additional information;
2. Verify product specifications and make a sample;
3. Send the sample out until the clients receive it and verify it;
4. After samples are confirmed, we will send the customer an invoice along with the shipping, and they will need to pay;
5. We begin producing orders in quantity;
6. After the order is complete, we get in touch with the agent or forwarder and set up shipping.

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