Gynostemma Extract

Gynostemma Extract is a natural plant extract derived from the leaves and stems of Gynostemma pentaphyllum, a climbing perennial herb native to East Asia (China, Japan, Korea) and Southeast Asia. Its key active components are gynostemma saponins (gypenosides), a group of triterpenoid saponins structurally similar to ginsenosides (active compounds in ginseng), with over 80 identified gypenosides (e.g., gypenoside IV, VII, XLIX) as the primary bioactive markers. The extract's molecular formula varies by specific gypenoside, with an average molecular weight range of 400–800 g/mol, and its CAS number (for the standardized extract) is 90057-91-5. It typically appears as a light yellow to brown fine powder, with a characteristic herbal odor and bitter taste. It is soluble in water, ethanol, and aqueous glycerin, and stable under storage conditions of cool (15–25°C), dry, and away from direct sunlight. Commercial formulations include research-grade (≥98% purity), food-grade (≥95% purity), and supplement-grade extracts, with standardizations available for specific gypenoside contents (e.g., 20%, 40%, 80% gypenosides) based on application needs.

Main Active Ingredient: Gypenosides (Standard specs: 20%, 40%, 80%, 98% UV/HPLC)

Appearance: Brownish-yellow to light yellow fine powder

CAS No.: 15588-38-2 (Gypenoside)

Plant Part Used: Leaf & Stem

1. Adaptogenic & Stress Relief: As a natural adaptogen, it helps the body adapt to physical and psychological stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol levels, and enhancing resilience to stress-induced fatigue.
2. Antioxidant & Anti-Aging Support: Gypenosides scavenge free radicals (e.g., reactive oxygen species, ROS) and inhibit lipid peroxidation, protecting cells from oxidative damage. It also promotes the activity of antioxidant enzymes (SOD, CAT, GSH-Px), supporting skin health and slowing age-related cellular decline.
3. Cardiovascular Health Promotion: It helps regulate healthy blood lipid levels by reducing LDL ("bad" cholesterol) and triglycerides while increasing HDL ("good" cholesterol). It also supports healthy blood pressure by relaxing vascular smooth muscles and improving blood circulation.
4. Immune System Modulation: It enhances immune function by stimulating the proliferation and activity of immune cells (lymphocytes, macrophages, natural killer cells) and regulating the production of cytokines (IL-2, IFN-γ), strengthening the body's defense against pathogens.
5. Metabolic & Energy Support: It aids in glucose metabolism by improving insulin sensitivity, helping maintain healthy blood sugar levels. Additionally, it boosts mitochondrial function, enhancing cellular energy production and reducing feelings of fatigue.

1. Dietary Supplements: It is widely used in oral supplements (capsules, tablets, powders, liquid extracts) as an adaptogenic, anti-aging, and cardiovascular support ingredient. It is often marketed as a "natural ginseng alternative" due to its ginsenoside-like properties.
2. Functional Foods & Beverages: It is incorporated into functional drinks (herbal teas, energy drinks, health tonics), snacks, and fortified foods (cereals, bars) to add antioxidant, metabolic, and stress-relief benefits.
3. Cosmetics & Skincare: It is used in skincare products (serums, creams, masks, toners) for its antioxidant, anti-inflammatory, and moisturizing effects. It helps reduce skin dullness, fine lines, and UV-induced damage, while soothing irritated skin.
4. Pharmaceutical Research: Researchers utilize Gynostemma Extract in preclinical and clinical studies exploring its potential in treating metabolic disorders (diabetes, dyslipidemia), cardiovascular diseases, and age-related cognitive decline. It is also investigated for its antiinflammatory and anticancer properties (inhibition of tumor cell proliferation in vitro).
5. Traditional Medicine & Wellness: In Traditional Chinese Medicine (TCM), it is used to "clear heat, detoxify, and invigorate qi," and modern wellness practices adopt it for holistic stress management and overall vitality support.

OEM&ODM

We offer a variety of dosage forms and neutral packaging, including mixed powders, granules, soft capsules, hard capsules, tablets, gummies, and more, to meet the diverse needs of our customers. Yinao is committed to providing customers with natural, safe, and organic plant extracts.

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1. More Than 15 Years Botanical Extract Supplier, and around 2000 kinds of products!

2. Focused on the development of plant active ingredients for more than 15 years and has a number of national invention patents.

3. International certification system: ISO9001, ISO22000, IP (non GMO), Jewish, halal, organic and other certification.

4. Professional and experienced r&d team: professors from famous universities and experts with decades of working experience in this industry.

5. Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

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