Genistein 98%

Genistein 98%

Genistein 98% | Natural & Synthetic Sources | Women’s Health Core Ingredient
Product name: Genistein
Other name: Sophora Fruit Extract
CAS No.: 446-72-0
MF: C15H10O5
MW: 270.24
Appearance: Yellow powder
Specification: 98%
Type: Herbal extract
Package: 1kg/foil bag, 25kgs/Drum, or as per different spec.

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Product Introduction

Product introduction

Genistein is a natural flavonoid compound mainly derived from leguminous plants such as soybeans and chickpeas, with various biological activities and application values.

Test Item

Specification

Typical Result

Test Method

Assay (Genistein)

≥98.0%

98.62%

HPLC (External Standard Method)

Free Aglycone Content

≥97.5%

97.89%

HPLC

Appearance

Pale yellow to off-white fine powder

Complies

Organoleptic

Odor & Taste

Characteristic mild soy-like odor, slightly bitter

Complies

Organoleptic

Particle Size

NLT 95% pass 100 mesh

Complies

EP 8.0 <2.9.12>

Loss on Drying

≤3.00%

2.15%

EP 8.0 <2.2.32>

Residue on Ignition

≤0.50%

0.32%

EP 8.0 <2.4.16>

Heavy Metals (Pb)

≤5 mg/kg

<5 mg/kg

ICP-MS

Arsenic (As)

≤1 mg/kg

<1 mg/kg

ICP-MS

Microbial Count

Total Aerobic Bacteria ≤500 CFU/g

180 CFU/g

USP 45-NF 40

Yeast & Mold

≤50 CFU/g

12 CFU/g

USP 45-NF 40

E. coli

Negative

Negative

USP 45-NF 40

Salmonella

Negative (in 10g sample)

Negative

USP 45-NF 40

Extract Solvent

Supercritical CO₂ & Ethanol (food grade), No Residue

Complies

GC-MS

Expiry Date

24 Months (Stored in Sealed, Cool & Dry Place, Away from Light)

Complies

Stability Test (Accelerated & Long-Term)

Active Ingredients

The core value of our Genistein 98% lies in its ultra-high purity and targeted active composition, setting it apart from conventional isoflavone blends that dilute genistein with other less effective compounds. We prioritize the bioactive, free aglycone form of genistein-unlike most products that contain bound glycosides (which require intestinal hydrolysis to become active)-ensuring immediate efficacy:

  • Genistein (Free Aglycone): The primary active component, with a guaranteed 98% concentration (min. 98.0%, max. 99.5%). This is the bioactive form of genistein (5,7,4'-trihydroxyisoflavone), a natural plant estrogen (phytoestrogen) with a molecular structure similar to human estrogen, enabling it to bind to estrogen receptors (ERα and ERβ) and exert balanced hormonal effects. Unlike glycosylated genistein (e.g., genistin), our free aglycone form is directly absorbed by the intestinal tract without needing to be broken down, delivering faster and more consistent results.
  • Minor Bioactive Isoflavones: Trace amounts (≤2%) of naturally occurring co-isoflavones, including daidzein and glycitein, which work synergistically with genistein to enhance its overall efficacy. These minor components are retained intentionally to mimic the natural isoflavone profile of soybeans, supporting holistic health benefits without diluting the core genistein concentration.
  • Natural Antioxidant Co-Factors: Small quantities of soy-derived phenols and trace minerals (e.g., magnesium, zinc) that complement genistein's antioxidant activity, protecting cells from oxidative damage and amplifying its anti-aging effects. These co-factors are naturally present in the raw soybean source and preserved during our gentle extraction process.
  • Simply put, our Genistein 98% focuses on quality over quantity-prioritizing the most bioactive form of genistein at the highest purity, rather than filling the product with inactive ingredients or diluted blends.

Source Transparency: Natural vs. Synthetic

We at TIANJIN YINAO are aware that various formulas have various label specifications. To fit the positioning of your business, we provide both quality sources of genistein.

Feature Natural Genistein Synthetic Genistein
Origin Extracted from Sophora japonica (standard) or Soy. Chemical synthesis (identical molecular structure).
Purity Standardized to ≥≥ 98% (HPLC). Ultra-high purity, typically ≥≥ 99%.
B2B Benefit Ideal for "Plant-based" and "Clean Label" brands. Most cost-effective for large-scale industrial supply.
Traceability Full botanical identification provided. Consistent batch-to-batch stability.

Women's Health Application Cases

Genistein is a potent isoflavone that acts as a natural selective estrogen receptor modulator (SERM). It is an essential component of sophisticated women's health practices.

Menopause Management (Hormonal Balance)

Objective: Reduction of hot flashes and night sweats.

Synergy: Combine Genistein with Black Cohosh Extract or Red Clover Isoflavones.

Formulation Logic: Without the dangers of synthetic hormone replacement, genistein relieves menopausal symptoms by binding to ER-β receptors.

 

Bone Density & Osteoporosis Support

Objective: Prevention of postmenopausal bone loss.

Synergy: Pair Genistein with Vitamin D3, Vitamin K2 (MK-7), and Calcium AEP.

Formulation Logic: According to clinical research, genistein inhibits bone resorption while increasing osteoblast activity, or bone-forming cells.

 

Function

  1. Anticancer effect: It can induce tumor cell apoptosis by inhibiting tyrosine protein kinase (PTK) and topoisomerase, and inhibit breast cancer, prostate cancer, etc.
  2. Cardiovascular protection: Regulating hormone receptor signaling pathways to improve cardiovascular health.
  3. Neuroprotection: By activating the PI3K/Akt signaling pathway, it improves neuronal damage caused by high glucose.
  4. Other applications: As a dietary supplement, improve menopausal symptoms and prevent osteoporosis.

Capture R&D Interest: Free Samples Available

We assist you in the process of developing new products. We provide specialized sample units for institutional R&D so you may verify our quality in your lab.

Sample Specification: 1g - 5g high-purity Genistein.

Fast Dispatch: Sent via DHL/FedEx with full COA ;

Tech Support: Direct access to our chemists for solubility and stability queries.    [REQUEST FREE SAMPLES FOR R&D]

OEM&ODM

To fully meet the diverse needs of our clients, we offer a wide range of dosage forms and neutral packaging services, including mixed powders, granules, soft and hard capsules, tablets, and gummies. Inno is committed to providing our clients with organic, safe, and natural plant extract products.

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Gummy
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Granular
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Blending Powder
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Capsules(Hard Capsules & Soft Capsules)
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Tablet & Effervescent Tablet
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Liquid and o

Delivery & Shipping &Package

International Express-- Fedex/DHL/UPS, air shipping and sea shipping, double-clearance custom.

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Packaging Details

10g/Bag,1Kg/bag/25kg/Drum,According to your requirements

Port

China main port

 

Why Choose Us?

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We are a strong plant extract supplier with over 15 years of professional experience and nearly 2,000 products. Our company focuses on the research and development of plant active ingredients and has obtained multiple national invention patents. We possess comprehensive international certifications, such as ISO9001, ISO22000, non-GMO, kosher, and organic certifications. Our R&D team is led by renowned scholars and industry experts, and our products are widely used by major international brands, covering multiple important sectors.

FAQ

Q: Can I buy just 1 kg to try it out?

A: For many high-value products, 1 kg perfectly meets our MOQ requirement. Please feel free to inquire about the MOQ information for specific products.

Q: Are there discounts for large purchase quantities?

A: We implement tiered pricing; the larger the purchase volume, the more favorable the unit price you will receive.

Q: Does the price vary depending on the purchase quantity?

A: Yes, our prices are flexible. Different purchase quantities correspond to different unit prices, and larger orders naturally enjoy better prices.

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